Irresistibly Cheesy Spicy Southern Chicken Spaghetti Casserole

Enjoy the irresistible Spicy Southern Cheesy Chicken Spaghetti Casserole, a comforting dish perfect for gatherings.

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Course: Comfort Food

Cuisine: Southern

Keyword: casserole, Cheesy Chicken, Comfort Food, Easy Recipe, Quick Meal, Spicy Southern Cheesy Chicken Spaghetti Casserole

Prep Time: 15

Cook Time: 30

Resting Time: 5

Total Time: 50

Servings: servings

Calories: 550kcal

2 lbs Chicken Breasts Can substitute with shrimp or mushrooms for a vegetarian option.
8 oz Spaghetti Feel free to use any other pasta as a substitute.
2 cups Shredded Sharp Cheddar Cheese Consider a blend like mozzarella for a different twist.
1 cup Fresh Bell Peppers Can swap for zucchini or spinach.
1 can Cream of Chicken Soup A homemade or vegetarian alternative works great too.
1 tbsp Paprika Smoked paprika can give it a delicious smoky flavor.
1/2 tsp Cayenne Pepper Adjust based on your spice preference.
1 tsp Garlic Powder Fresh minced garlic can provide a fresher flavor profile.
1/4 cup Green Onions Use as a garnish.

Preheat your oven to 350°F (175°C) and generously grease a large casserole dish.
Cook the boneless chicken breasts in a pot over medium heat for about 6-7 minutes per side until fully cooked.
Boil salted water in a large pot; cook the spaghetti until al dente, about 8-10 minutes. Drain and set aside.
Mix in a large mixing bowl the shredded chicken, cooked spaghetti, cream of chicken soup, bell peppers, spices, and half of the cheddar cheese.
Transfer the mixture to your greased casserole dish, spreading it evenly. Top with the remaining cheddar cheese.
Bake for 25-30 minutes until bubbly and golden brown.
Rest the casserole for about 5 minutes before serving.

Serve with a crisp side salad for a refreshing balance.